• artifex@piefed.social
    link
    fedilink
    English
    arrow-up
    158
    ·
    3 days ago

    Remember folks, taking too much Tylenol WILL destroy your liver and kill you fairly quickly.

    • 9point6@lemmy.world
      link
      fedilink
      English
      arrow-up
      64
      arrow-down
      1
      ·
      3 days ago

      And don’t take it the morning after a heavy night of drinking, it’s like 10x more toxic in that scenario.

      If you need a pain killer go for ibuprofen until like 24h after you finished your last drink

        • Mouselemming@sh.itjust.works
          link
          fedilink
          English
          arrow-up
          25
          ·
          3 days ago

          Tylenol and alcohol are both processed through the liver and can harm it, especially when taken together, whereas ibuprofen …

          Okay I went to Wikipedia to check on the safety of ibuprofen with alcohol (bad idea, can cause gastric bleeding, just don’t combine painkillers and booze in general) and I found out two (2) different things I found very interesting:

          “Unlike most other NSAIDs, ibuprofen also acts as an inhibitor of Rho kinase and may be useful in recovery from spinal cord injury.[59][60] Another unusual activity is inhibition of the sweet taste receptor.[61]”

          Hopefully I’ll not need the first fact, but I’m all for anything that helps those who do.

          And as a person with weight issues it’s useful to me to know that second one so I don’t sabotage myself!

          • 9point6@lemmy.world
            link
            fedilink
            English
            arrow-up
            10
            ·
            edit-2
            3 days ago

            Yeah that’s a good call, definitely don’t smash the ibuprofen, but I think one dose is generally pretty low risk, given I believe you still need to be overdosing on the ibuprofen to get problems, at least that’s what a doctor told me when I asked a number of years ago.

            The thing with alcohol and paracetamol/acetaminophen is it causes your liver to do something different than if you had the two separately. I’m not 100% I’m getting the terminology exactly right here but, If alcohol is taking up all of the “usual” enzyme a less efficient enzyme processes the paracetamol that’s less efficient at metabolising it, that enzyme produces a toxic by-product that normally isn’t created. That toxic by-product is what causes the liver failure if it can’t subsequently be metabolised again quick enough.

          • kerrigan778@lemmy.blahaj.zone
            link
            fedilink
            English
            arrow-up
            4
            ·
            edit-2
            3 days ago

            A lot of things increase your risk of GI bleeding, it is a very serious danger but it’s something you have to look at combinations of risk factors. I take high dose zoloft which increases my risk of GI bleeding and I drink socially, I never take more than a fairly low dose of ibuprofen or aspirin after drinking and I never take more than 200 mg of ibuprofen every 2 hours when not drinking, so far so good.

            • BeeegScaaawyCripple@lemmy.world
              link
              fedilink
              English
              arrow-up
              3
              ·
              edit-2
              2 days ago

              iirc the GI bleed risk is a standard NSAID thing. They cause your gastric and intestinal linings to grow slower, and since you need to constantly replenish that mucus. if it’s not thick enough you get an ulcer.

              standard not a doctor this isn’t medical advice blahblah

        • jaybone@lemmy.zip
          link
          fedilink
          English
          arrow-up
          8
          ·
          3 days ago

          It can damage your liver. Though some say it is greatly exaggerated when this discussion pops up online. But still I wouldn’t risk it.

          I think advil/motrin is a safer NSAID if you are a drinker.

    • mic_check_one_two@lemmy.dbzer0.com
      link
      fedilink
      English
      arrow-up
      31
      ·
      3 days ago

      Correction: It will start killing you quickly, but the actual death will be long and painful. Liver failure is a particularly bad way to go out.

      • fuckgod@feddit.online
        link
        fedilink
        English
        arrow-up
        7
        ·
        3 days ago

        Man, Trump looks like he could use a night out drinking and then hangover relief with Tylenol.

    • criss_cross@lemmy.world
      link
      fedilink
      English
      arrow-up
      14
      ·
      3 days ago

      My favorite stat about the safety seals is that you’re much more likely to die taking Tylenol than from someone poisoning your Tylenol.

    • Jorunn@piefed.blahaj.zoneOPM
      link
      fedilink
      English
      arrow-up
      15
      ·
      2 days ago

      Doctors and scientists in my country assured everyone that paracetamol (tylenol) is fine and to ignore whatever the US is doing :P

      But for your information Trump announced that paracetamol during pregnancy causes autism.

          • CheesyFox@lemmy.sdf.org
            link
            fedilink
            English
            arrow-up
            2
            ·
            2 days ago

            i’m afraid, our biggest concern should be a dangerous airborne chemical compound, called dioxygen. It spreads everywhere, and autism is on the mild side of possible effects caused by this lethal chemical weapon. I heard it even caused a great extinction once.

    • OldChicoAle@lemmy.world
      link
      fedilink
      English
      arrow-up
      12
      arrow-down
      1
      ·
      edit-2
      3 days ago

      Hot take: Americans don’t know how dangerous this is. Every day I am reminded just how fucking dumb the average American is. A land of degrading intelligence. Our president loves the poorly educated, just like our elected officials do!

  • Geodad@lemmy.world
    link
    fedilink
    English
    arrow-up
    5
    arrow-down
    5
    ·
    2 days ago

    That’s enough tylenol to do massive damage to your liver, if taken in a single dose. It would likely put you in the hospital or kill you.

    • No, it wouldn’t. These are likely 500mg pills, and there’s 7 of them. That’s 3.5g worth, well below the daily recommended limit of 4g and well below the 10g single dose limit for adults where toxicity becomes likely. Even if these were the chonky 1g pills, it’s not likely to cause liver damage.

    • Phineaz@feddit.org
      link
      fedilink
      English
      arrow-up
      2
      ·
      2 days ago

      Depends on the concentration. Yes Paracetamol can absolutely kill you if taken in grand excess. But this would have to be a very high dosage per pill to get you that far. Still not healthy of course.